Riboflavin

Riboflavin Monograph

Introduction Riboflavin was originally recognized as a growth factor in 1879 and named vitamin B2 according to the British nomenclature system. It was first isolated from egg whites in 1934 and synthesized in 1935.1,2 Riboflavin fluoresces yellow-orange and gives the yellow-white hue to egg whites and milk. Riboflavin has two active coenzyme forms, riboflavin 5’-phosphate (R5P; flavin mononucle...

Regulation of riboflavin-metabolizing enzymes in riboflavin deficiency.

FASS, STEVEN, AND RICHARD S. RIVLIN. Regulation of riboflavinmetabolizing enzymes in ribuj?auin de_ficiency. Am, J. Physiol. 217(4) : 988-99 1. 1969.-The effects of riboflavin deficiency in rats on the hepatic activities of flavokinase, FAD pyrophosphorylase, and FMN phosphatase, three enzymes involved in riboflavin metabolism, have been measured and compared to the hepatic concentrations of FA...

Chemical determination of riboflavin.

Riboflavin Production by Molds.

A bacterial riboflavin hydrolase.

Riboflavin is known to be decomposed by specific bacteria. Foster (1,2) showed that the ribityl portion of riboflavin was oxidized by living cells of Pseudomonas ribo$avina, leaving the heterocyclic ring, 7, %dimethylalloxazine (lumichrome), intact. Later, Hou (3) found that lumichrome accumulated as riboflavin disappeared in a culture of tubercle bacilli to which the vitamin had been added. Th...